Cisplatin lagerung

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August undefined, 2024

WebJun 13, 2005 · Cisplatin, cisplatinum or cis-diamminedichloroplatinum (II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including … WebMaterial Name: Cisplatin Solution for Injection - 0.5 and 1 mg/ml Trade Name: Platamine; Cisplatino; Cisplatine; Platiblastin; Plastisil; Platiblastin S Chemical Family: Mixture …

Cisplatin: Package Insert - Drugs.com

WebCisplatin is an intercalating agent that induces apoptosis of cancer cells, and it has been the most widely used drug in the first-line chemotherapy. However, the increase in … WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the generation of superoxide radicals. Nephrotoxicity is the most well-known and potentially most clinically significant toxicity. tsum with white hands

Overcoming cisplatin resistance of ovarian cancer cells by …

WebApr 6, 2024 · Cisplatin (Platinol) is an inorganic coordination complex with a broad range of antitumor activity. It is especially useful in the treatment of testicular and ovarian cancer. It binds to DNA at nucleophilic sites, such as the N7 and O6 of guanine, producing alterations in DNA structure and inhibition of DNA synthesis. WebApr 12, 2024 · Accord has cisplatin 1 mg/mL 50 mL and 100 mL vials on back order and the company cannot estimate a release date. Fresenius Kabi has cisplatin 1 mg/mL 50 mL, 100 mL, and 200 mL vials on back order and the company estimates a release date of mid-April 2024 for the 50 mL vials and mid- to late-April 2024 for the 100 mL and 200 mL vials. WebApr 5, 2024 · Cisplatin for injection has been administered at 20 mg/m 2 intravenously daily for 5 days per cycle. Other doses and combination regimens have been used. Advanced … phly surety

Cisplatin 12. Modes of Action of Cisplatin - Chemistry LibreTexts

WebMar 24, 2016 · The encapsulated cisplatin concentration measured by HPLC was 1.2 mg/mL, which is close to the concentration of conventional cisplatin formulations. The lipid concentration (25.39 ± 4.06 mg/mL) was considered safe and did not cause any observable toxicity in animals. WebCisplatin Injection infusion concentrate is a clear, colorless, sterile aqueous solution available in amber vials. Each 50 mL or 100 mL amber vial of infusion concentrate … phly special events portalWebFeb 16, 2024 · Generic name: cisplatin [ sis-PLA-tin ] Brand names: Platinol, Platinol-AQ, Platinol (Restricted Access) Dosage forms: intravenous powder for injection (50 mg), intravenous solution (1 mg/mL) Drug class: Alkylating agents Medically reviewed by Drugs.com on Feb 16, 2024. Written by Cerner Multum. Uses Warnings Before taking … tsun 550w

"WebApr 1, 2016 · By using two pairs of genetically matched cisplatin-sensitive and cisplatin-resistant ovarian cancer cell lines, we tested the hypothesis that downregulating hypoxia-inducible factor-1 (HIF-1), which regulates metabolic enzymes involved in glycolysis, is a promising strategy for overcoming cisplatin resistance of human ovarian cancer cells. " - Cisplatin lagerung

Cisplatin lagerung

Cisplatin (Intravenous Route) Side Effects - Mayo Clinic

WebCisplatin is a platinum chemotherapeutic used in a variety of malignancies. The antineoplastic activity occurs from DNA cross-links and adducts, in addition to the … WebCisplatin adducts are Guanine-Guanine (GG) DNA intrastrand cross links caused by the chemical compound Cisplatin. Cisplatin is used as a chemotherapy agent that contains …

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WebAug 8, 2010 · Cisplatin is one of the most effective anticancer agents widely used in the treatment of solid tumors. It is generally considered as a cytotoxic drug which kills cancer … WebCisplatin is administered to cancer patients intravenously as a sterile saline solution (that is, containing salt—specifically, sodium chloride). Once cisplatin is in the bloodstream, it remains intact due the relatively high concentration of chloride ions (~100 mM).

WebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class of cytotoxic medications. This activity reviews the indications, action, and contraindications for cisplatinum as a valuable agent in treating malignancy. WebDie Heilwirkung erfordert eine von der Tumorart und Fraktionierung abhängige Gesamtdosis von 20 bis 80 Gray, die in Abhängigkeit vom Behandlungsschema in einer Sitzung oder über mehrere Wochen verteilt verabreicht wird.

Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g., small cell lung cancer, squamous cell carcinoma of the head and neck and ovarian cancer), lymphomas, bladder cancer, cervical cancer, and germ cell tumors. Because of its widespread use, the cure rate for testicular cancer has increased from 10% to 85… WebFeb 1, 2024 · Cisplatin injection is used to treat advanced cancer of the bladder, ovaries, or testicles. Cisplatin is an antineoplastic agent (cancer medicine). It interferes with the …

WebDec 12, 2024 · Cisplatin Adult Medication Share This information from Lexicomp ® explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider. Warning This drug may cause kidney problems like kidney failure.

WebOct 22, 2024 · Cisplatin is an alkylating agent which induces DNA damage through the formation of cisplatin-DNA adducts, leading to cell cycle arrest and apoptosis. In the management of advanced OSCC, cisplatin-based chemotherapy or chemoradiotherapy has been considered as the first-line treatment. tsu my web loginWebFeb 17, 2024 · Cisplatin inhibits DNA synthesis by the formation of DNA cross-links; denatures the double helix; covalently binds to DNA bases and disrupts DNA function; may also bind to proteins; the cis -isomer is 14 … phlysupport phly.comWebPRODUCT INFORMATION – DBL™ CISPLATIN INJECTION(CISPLATIN) 1. NAME OF THE MEDICINE Cisplatin 2. QUALITATIVE AND QUANTITATIVE COMPOSITION … phly tracWebCisplatin is an antineoplastic drug used for the treatment of cancer patients with a variety of different malignancies. Application Cisplatin may be used as an analytical reference standard for the determination of the analyte in plasma, cancer cell, and tumor samples by high-performance liquid chromatographic assay. phly senseWebSep 18, 2024 · Cisplatin is a medication used to manage and treat solid tumors and hematologic malignancies. It is in the alkylating agent class of cytotoxic medications. This activity reviews the indications, action, and … phly profesional liability insurance phly wirelessWebMaterial Name: Cisplatin Freeze-Dried Powder for Injection Trade Name: Platamine; Cisplatino; Platiblastin; Platistin Chemical Family: Mixture Intended Use: Pharmaceutical … phly stock