Cisplatin or carboplatin

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August undefined, 2024

WebJul 19, 2016 · Carboplatin yielded comparable results to cisplatin in concurrent chemo-radiation for locally advanced cervical cancer. In addition, carboplatin was associated with a better compliance rate and was associated with less of anemia, neutropenia and nephrotoxicity. Peer Review reports Backgrounds WebApr 16, 2024 · All four planned doses of cisplatin or carboplatin were received by 82.5% of the patients in the pembrolizumab-combination group and by 74.3% of those in the placebo-combination group; 76.5% and...

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WebMar 23, 2015 · The recommendation to administer gemcitabine prior to cisplatin is based on results of phase 1 studies in adults with solid tumors, which indicated that this administration schedule may increase... WebChemoradiotherapy with paclitaxel liposome plus cisplatin for locally advanced esophageal squamous cell carcinoma: A retrospective analysis ... (TF), and paclitaxel and carboplatin (TC) schemes, which did not show significant survival benefits. 7 , 10 , 12 Currently, paclitaxel‐based chemotherapy is a concurrent regimen commonly used in clinics. song night train

Docetaxel maintenance therapy versus best supportive care after …

WebCarboplatin / pharmacology Cisplatin / metabolism Cisplatin / pharmacology* Cisplatin / therapeutic use DNA / drug effects Drug Resistance / genetics Gene Expression Regulation, Neoplastic / drug effects ... WebJul 1, 2000 · Carboplatin provides an improved therapeutic index compared to cisplatin, especially in terms of reduced nonhematologic toxicities. However, added hematologic toxicity may be problematic when combining carboplatin with other myelosuppressive chemotherapeutic agents. WebIncluded trials evaluated etoposide, mitomycin with vindesine or vinblastine, cisplatin or carboplatin with paclitaxel, docetaxel, gemcitabine, or cisplatin and carboplatin in combination with tirapazamine. Doses varied between trials. The median number of … song nikki by burt bacharach

Carboplatin versus cisplatin in combination with etoposide in the …

Cisplatin and carboplatin result in similar gonadotoxicity …

WebSep 12, 2024 · While physicians may use cisplatin and carboplatin for lung or ovarian cancer, cisplatin is also used to treat bladder and testicular cancer. The ordinary dosage of carboplatin is up to three times higher than that of cisplatin in many cases, but the … WebMar 30, 2024 · FDA approves durvalumab for extensive-stage small cell lung cancer On March 27, 2024, the Food and Drug Administration approved durvalumab (IMFINZI, AstraZeneca) in combination with etoposide and... song nobody called todayWebMay 29, 2024 · For the first 4 cycles, participants also received etoposide 100 mg/m 2 on days 1, 2, and 3 and the investigator’s choice of carboplatin area under the plasma drug concentration-time curve 5 or cisplatin 75 … song noah built the ark

"WebWe investigated the activity and safety of first-line GEMOX compared with gemcitabine–carboplatin (GCb) in cisplatin-ineligible patients with advanced UCC. Methods: Treatment-naive, cisplatin-ineligible patients with advanced UCC were … " - Cisplatin or carboplatin

Cisplatin or carboplatin

What Is the Difference between Cisplatin and Carboplatin?

WebMay 10, 2012 · Carboplatin- or cisplatin-based chemotherapy in first-line treatment of small-cell lung cancer: the COCIS meta-analysis of individual patient data. Our meta-analysis of individual patient data suggests no differences in efficacy between cisplatin … WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel …

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WebWe investigated the activity and safety of first-line GEMOX compared with gemcitabine–carboplatin (GCb) in cisplatin-ineligible patients with advanced UCC. Methods: Treatment-naive, cisplatin-ineligible patients with advanced UCC were randomly assigned to GEMOX (gemcitabine 1000 mg/m 2 , oxaliplatin 100 mg/m 2 on day 1 [D1] … WebFeb 28, 2024 · The EP regimen (etoposide plus cisplatin), in particular, is the most frequently used chemotherapy regimen for initial treatment.4Carboplatin is also frequently used clinically as a replacement of cisplatin to reduce vomiting, neurotoxicity, and nephrotoxicity, but similarly it increases the risk of myelosuppression.

WebDec 19, 2024 · Platinum-doublet chemotherapy consists of the following: Paclitaxel 175-200 mg/m 2 and carboplatin area under the curve (AUC) 5 or 6 (any histology) or Pemetrexed 500 mg/m 2 and cisplatin 75... WebUsually, the combination includes a type of chemo drug called a platinum compound (usually cisplatin or carboplatin), and another type of chemo drug called a taxane, such as paclitaxel (Taxol ®) or docetaxel (Taxotere ® ). These drugs are usually given as an IV (put into a vein) every 3 to 4 weeks.

WebExperiences with cisplatin and carboplatin are summarized in this paper. The treatment response to monotherapy with cisplatin or carboplatin was proved in non-Hodgkin's lymphomas. This is necessary condition for the application of the drug in … WebDec 1, 2024 · Docetaxel maintenance therapy versus best supportive care after first-line chemotherapy with different dose docetaxel plus cisplatin for advanced non-small cell lung cancer (TFINE study, CTONG-0904): an open-label, randomized, phase III trial - PMC Back to Top Skip to main content An official website of the United States government

WebHowever, the toxicity of carboplatin was smaller than that of cisplatin in proximal tubular epithelial cells that had been preincubated with AGEs. Yokoo et al reported that carboplatin is not transported by organic cation transporter and MATE1/SLC47A1; 29 thus, the toxicity of carboplatin was not affected by decreasing the expression of MATE1 ...

WebFeb 28, 2024 · The EP regimen (etoposide plus cisplatin), in particular, is the most frequently used chemotherapy regimen for initial treatment. 4 Carboplatin is also frequently used clinically as a replacement of cisplatin to reduce vomiting, neurotoxicity, and … smallest pga playerWebBoth chemo drugs are hard on the bone marrow & kidneys--they both cause neuropathy & can cause hearing loss. The carboplatin is a little more gentle on the kidneys so you must have good kidneys. For sure, you should drink a lot of water before & after chemo … smallest pets you can own smallest pet snake to ownWebHowever, the toxicity of carboplatin was smaller than that of cisplatin in proximal tubular epithelial cells that had been preincubated with AGEs. Yokoo et al reported that carboplatin is not transported by organic cation transporter and MATE1/SLC47A1; 29 thus, the … smallest pet rabbit breedWebOct 20, 2024 · Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years’ follow-up. … song nobody else but youWebOct 14, 2024 · The key difference between carboplatin and cisplatin is that carboplatin shows less consistent survival advantages, whereas cisplatin shows more consistent survival advantages in meta-analyses of … smallest pet cat in the worldWebCarboplatin is an anticancer drug ("antineoplastic" or "cytotoxic") chemotherapy drug. Carboplatin is classified as an "alkylating agent." What Carboplatin Is Used For: Carboplatin is used to treat ovarian cancer. Carboplatin is also used for other types of … smallest pet in the world