Cyf1p2

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August undefined, 2024

WebNov 8, 2024 · This unveiled an underlying relationship between genetic inheritance and eating behaviors. That is, researchers found a causal link between a mutation in the gene CYFIP2 and binge eating behaviors (Goldberg, 2024). In short, these results indicate that there may be major genetic risk factors for developing BED in addition to sociocultural ... WebCYFIP1/2 belongs to the CYFIP family and is involved in T-cell adhesion and p53-dependent induction of apoptosis. CYFIP1 contains 1,253 amino acids and shares 88% sequence identity with CYFIP2. CYFIP1 and CYFIP2 are members of a highly conserved protein family and share approximately 99% sequence identity with their mouse orthologs.

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WebAnti CYFIP2 pAb [Catalog No.: ATL-HPA071459] Toggle menu. Compare ; Phone: 760-431-4600 / Fax: 760-431-4604; Sign in or Register; Cart 0. Search. CURRENT PROMOTIONS. WORLDWIDE DISTRIBUTION. CONTACT US. Neurodegeneration Products; CUSABIO dashboard; Fukushima Cancer Gene Overexpressing Cell Lines; Cytoplasmic FMR1-interacting protein 2 is a protein that in humans is encoded by the CYFIP2 gene. Cytoplasmic FMR1 interacting protein is a 1253 amino acid long protein and is highly conserved sharing 99% sequence identity to the mouse protein. It is expressed mainly in brain tissues, white blood cells and the kidney. shane warnes ball of the century

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WebOct 29, 2024 · The cytoplasmic fragile X mental retardation 1 (FMR1)-interacting protein 2 (CYFIP2) gene is associated with epilepsy, intellectual disability (ID), and developmental delay, suggesting its critical role in proper neuronal development and function. CYFIP2 is involved in regulating cellular actin dynamics and also interacts with RNA-binding … WebDec 21, 2024 · Alzheimer’s disease (AD) is characterised by Aβ and tau pathology as well as synaptic degeneration. Recently, it was suggested that the development of these key disease features may at least in part be due to increased protein synthesis that is regulated by fragile X mental retardation protein (FMRP) and its binding partner CYFIP2. Using an … WebCYFIP1 has been shown to interact with FMR1, [5] to the exclusion of FXR1 and FXR2. [5] It also forms part of the WAVE regulatory complex (WRC), [7] and based on the crystal … shane warne rr

CYFIP1/2 antibody (16011-1-AP) Proteintech - ptglab

WebMar 6, 2007 · Component of the WAVE1 complex composed of ABI2, CYFIP2, BRK1, NCKAP1 and WASF1/WAVE1. Interacts with FMR1, FXR1 and FXR2 (By similarity). Interacts with FMR1 isoform 6; the interaction occurs in a RNA-dependent manner (PubMed:24658146). Interacts with RAC1 (activated form) which causes the complex to … WebCYFIP2, encoding the evolutionary highly conserved cytoplasmic FMRP interacting protein 2, has previously been proposed as a candidate gene for intellectual disability and … shane warner esqWebJan 21, 2024 · CYFIP2, encoding the evolutionary highly conserved cytoplasmic FMRP interacting protein 2, has previously been proposed as a candidate gene for intellectual … shane warne scandle

"WebOct 26, 2016 · Researchers have identified a gene ( CYFIP2) associated with binge eating. This finding represents one of the first examples of a genome-wide significant genetic factor to be identified for binge eating in … " - Cyf1p2

Cyf1p2

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WebMay 13, 2024 · 4.3164244635296499e-19. 4.9412745200703902e-19. 1.68047751266613e-18. 2.8198991731784599e-15. 3.5076328523240299e-13. 1.6381969761083399e-12. 3.0611919256070299e-12 WebNational Center for Biotechnology Information

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WebJan 9, 2024 · Cyfip2 was expressed highly in cortex, striatum, and hippocampus of wildtype mouse brain, and loss of 1 allele caused a layer-specific Cyfip2 decrease and F-actin (see 102610) increase in the medial prefrontal cortex (mPFC) of adult Cyfip2 +/- mice. F-actin is the key cytoskeletal component of excitatory synapses, and consequently, the F-actin ... WebCYFIP2 (Cytoplasmic FMR1-interacting protein 2, p53-inducible protein 121) is a 1,278 amino acid protein encoded by the human gene CYFIP2. CYFIP2 belongs to the CYFIP family and is involved in T-cell adhesion and p53 …

WebNov 24, 2024 · CYFIP1 and CYFIP2 have high amino acid sequence homology (88% identity and 95% similarity), suggesting similar functions at the molecular level. Specifically, both proteins interact with fragile X mental retardation protein (FMRP), an mRNA-binding protein whose loss causes fragile X syndrome (Schenck et al. 2001 ). WebSep 11, 2024 · Cyfip2 was expressed in the neuroblastic layer and ganglion cell layer (GCL) at embryonic day 13.5 (E13.5) and E17.5. After postnatal day 3 (P3), the Cyfip2 signal was restricted to the inner side of the retina. In contrast to Cyfip2, we did not detect significant signals of Cyfip1, an ortholog of Cyfip2, in the retina at all stages examined.

WebHere we find that CYFIP1 and CYFIP2 act non-redundantly during RGC axon development, with CYFIP2 specifically involved in axon sorting. Using in vivo and in vitro approaches, we report that CYFIP2 regulates RGC axon segregation by coordinating homotypic fasciculation and heterotypic repulsive responses. CYFIP2 associates and is co-transported with … WebMar 8, 2024 · Overview Product name Anti-CYFIP2 + CYFIP1 antibody [EPR17848-87] See all CYFIP2 + CYFIP1 primary antibodies Description Rabbit monoclonal [EPR17848-87] to CYFIP2 + CYFIP1 Host species Rabbit Tested applications Suitable for: IHC-P, WB, ICC/IF, Flow Cyt (Intra) more details Species reactivity Reacts with: Mouse, Human Immunogen

WebThis method allowed researchers the opportunity to identify any links between behavioral variations and genetic inheritance [1]. Through these efforts, researchers found a link between binge eating and a mutation in the gene known as cytoplasmic FMR1-interacting protein 2, or CYFIP2 [1].

WebApr 10, 2024 · 可以看到，读入的巨噬细胞数据已经过SCTransform()，结果储存在MP@assays[["SCT"]]中，使用正则化的负二项式模型 (regularized negative binomial model) 对UMI计数进行建模，以去除测序深度（每个细胞的总nUMI）引起的变异。与lognormalize归一化方法相比，集成了Normalizedata()，FindVariableFeatures()，ScaleData()三个函数 … shane warne siblings shane warne signed ballWebMar 21, 2024 · CYFIP2 (Cytoplasmic FMR1 Interacting Protein 2) is a Protein Coding gene. Diseases associated with CYFIP2 include Developmental And Epileptic Encephalopathy … shane warne retirementWebAug 13, 2024 · Variants of the cytoplasmic FMR1-interacting protein 2 (CYFIP2) gene are associated with early-onset epileptic encephalopathy, intellectual disability, and developmental delay.However, the current understanding of the molecular functions of CYFIP2 is limited to those related to actin dynamics, and thus, the detailed mechanisms … shane warne signatureWebShowing 25 of 6,421 results for CYFIP2 Search Time: 0 ms in Aliases & Descriptions Drugs & Compounds Disorders Text-Mined Disorders Domains Expression in Human Tissues Function Genomics Localization Orthologs Paralogs Pathways Phenotypes Proteins Publications Summaries Transcripts Variants NEW shane warne sky newsWebDec 4, 2024 · CYFIP2 cytoplasmic FMR1 interacting protein 2 [ (human)] Gene ID: 26999, updated on 22-Sep-2024 Summary Predicted to enable small GTPase binding activity. … shane warne signed bookWebJul 29, 2024 · CYFIP1 has been described as an eIF4E-binding protein (4E-BP), forming a posttranscriptional regulatory complex with FMRP in synaptoneurosomes and … shane warne sky sports